Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244830 | 0.68 | KDM4E (0.46) | KDM4EHTTLMNAMAPTCYP2D6 | |
| SCHEMBL471858 | 0.65 | KDM4E (0.60) | KDM4EHTTLMNAMAPTCYP2D6 | |
| SCHEMBL4462971 | 0.65 | KDM4E (0.55) | KDM4EHTTLMNAMAPTCYP2D6 | |
| SCHEMBL18380643 | 0.62 | KDM4E (0.61) | KDM4EHTTLMNAMAPTCYP2D6 | |
| SCHEMBL342910 | 0.60 | KDM4E (0.59) | KDM4EHTTLMNAMAPTCYP2D6 | |
| SCHEMBL15842842 | 0.60 | KDM4E (0.50) | KDM4EHTTLMNAMAPTCYP2D6 | |
| SCHEMBL15342923 | 0.60 | KDM4E (0.41) | KDM4EHTTLMNAMAPTCYP2D6 | |
| SCHEMBL15842513 | 0.60 | KDM4E (0.53) | KDM4EHTTLMNAMAPTCYP2D6 | |
| SCHEMBL8552733 | 0.60 | KDM4E (0.49) | KDM4EHTTLMNAMAPTCYP2D6 | |
| SCHEMBL15843192 | 0.60 | KDM4E (0.45) | KDM4EHTTLMNAMAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | claimed |
| CN-106559999-A | Hollow porous fiber | 金伯利-克拉克环球有限公司 | 2017-04-05 | — | — | CN | disclosed |