Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 7/20 | 0.82 |
| ▸ | KDR | P35968 | 1/20 | 0.75 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | CFTR | P13569 | 4/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 2/20 | 0.56 |
| ▸ | CCND1 | P24385 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372790 | 0.90 | BAZ2B (0.67) | BAZ2BKDRTRPV1CFTRHDAC1 | |
| SCHEMBL14521748 | 0.88 | BAZ2B (0.65) | BAZ2BKDRTRPV1CFTRHDAC1 | |
| SCHEMBL8401917 | 0.87 | BAZ2B (0.64) | BAZ2BKDRTRPV1CFTRHDAC1 | |
| SCHEMBL8111047 | 0.87 | BAZ2B (0.64) | BAZ2BKDRTRPV1CFTRHDAC1 | |
| SCHEMBL17037446 | 0.86 | BAZ2B (0.62) | BAZ2BKDRTRPV1CFTRHDAC1 | |
| SCHEMBL21588257 | 0.85 | BAZ2B (0.61) | BAZ2BKDRTRPV1CFTRHDAC1 | |
| SCHEMBL1867588 | 0.82 | BAZ2B (0.81) | BAZ2BKDRTRPV1LMNA | |
| SCHEMBL997329 | 0.82 | TRPV1 (0.67) | BAZ2BKDRTRPV1 | |
| SCHEMBL997366 | 0.81 | TRPV1 (0.66) | BAZ2BKDRTRPV1HDAC1HDAC6 | |
| SCHEMBL12083125 | 0.81 | CYP1A2 (0.78) | BAZ2BKDRHDAC1HDAC6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
| US-6048868-A | CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS; ANTIDEPRESSANTS | CEMAF (FR) | 2000-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | BAZ2B 1775/4885KDR 4855/4885TRPV1 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.