Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8035027 | 0.78 | KDM4E (0.31) | KDM4E | |
| SCHEMBL7359131 | 0.71 | KDM4E (0.39) | KDM4E | |
| SCHEMBL7359121 | 0.71 | KDM4E (0.34) | KDM4E | |
| SCHEMBL31194320 | 0.71 | — | — | |
| Bromide SCHEMBL8037664 | 0.70 | TP53 (0.37) | KDM4ETP53 | |
| Bromide SCHEMBL8023520 | 0.70 | KDM4E (0.34) | KDM4E | |
| SCHEMBL21254658 | 0.69 | — | — | |
| SCHEMBL23191118 | 0.68 | KDM4E (0.56) | KDM4ETP53 | |
| SCHEMBL8035302 | 0.67 | — | — | |
| SCHEMBL4231821 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022822-A | Organotin compound and catalyst for transesterification comprising the same | RYOJI NOYORI (JP) | 2000-02-08 | — | — | US | disclosed |