Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13481223 | 0.81 | — | — | |
| SCHEMBL25608540 | 0.81 | — | — | |
| SCHEMBL8033787 | 0.77 | TSHR (0.34) | CYP2D6ALDH1A1LMNATP53TSHR | |
| SCHEMBL12634649 | 0.73 | ELANE (0.34) | ALDH1A1LMNATP53TSHRCA1 | |
| SCHEMBL12634648 | 0.73 | POLB (0.34) | CYP2D6ALDH1A1LMNATP53TSHR | |
| SCHEMBL473531 | 0.72 | — | — | |
| SCHEMBL27803451 | 0.72 | CYP1A2 (0.31) | ALDH1A1LMNATP53TSHRCYP1A2 | |
| SCHEMBL320614 | 0.71 | — | — | |
| SCHEMBL6447862 | 0.71 | — | — | |
| SCHEMBL16974673 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180346739-A1 | POLYMERIC FLAME RETARDANT MIXTURES | CLARIANT PLASTICS & COATINGS LTD (CH) | 2018-12-06 | — | — | US | disclosed |
| EP-0548774-B1 | Process for producing a lactone or an ester | SUMITOMO CHEMICAL CO (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0537606-B1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| US-5405974-A | Reacting a ketone, oxygen, an aromatic aldehyde using an aromatic solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-11 | — | — | US | disclosed |
| US-5286875-A | Preparation of 5-hydroxyethylpyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| EP-0548774-A1 | Process for producing a lactone or an ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0537606-A1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF Aktiengesellschaft (DE) | 1993-04-21 | — | — | EP | disclosed |