SCHEMBL8038008

SCHEMBL8038008

C=CCCC1=CCC(C2CCC(c3ccc(Cl)cc3)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.33
HTR3A P46098 1/20 0.31
LSS P48449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8047742 0.88
SCHEMBL8049910 0.85 SRD5A1 (0.35) DRD2HTR3ALSS
SCHEMBL8049862 0.84 SPHK1 (0.37)
SCHEMBL8047929 0.84 PTGS1 (0.31)
SCHEMBL8049191 0.84 USP5 (0.30)
SCHEMBL8037462 0.84 HTR2C (0.39)
SCHEMBL8048836 0.84 GRIA1 (0.33)
SCHEMBL8052190 0.82 SPHK1 (0.35)
SCHEMBL8049022 0.82 HRH3 (0.33)
SCHEMBL8052398 0.82 HTR2C (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728829-B1 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-05-03 EP disclosed
US-5698136-A LOW TEMPERATURE COMPATIBILITY, CHEMICAL STABILITY CHISSO CORPORATION (JP) 1997-12-16 US disclosed
EP-0728829-A2 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1996-08-28 EP disclosed