Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 16/20 | 1.00 |
| ▸ | PRSS2 | P07478 | 16/20 | 1.00 |
| ▸ | PRSS3 | P35030 | 16/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873929 | 0.86 | F2 (0.75) | F2PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL1564090 | 0.81 | HTT (0.69) | F2PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL5448156 | 0.81 | HTT (0.69) | F2PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL10829745 | 0.81 | F2 (0.68) | F2PRSS1PRSS2PRSS3LMNA | |
| Sulfaguanidine SCHEMBL1650003 | 0.81 | F2 (1.00) | F2PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL22699663 | 0.81 | F2 (0.68) | F2PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL4028479 | 0.79 | F2 (0.66) | F2PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL10425537 | 0.78 | F2 (0.67) | F2PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL30873924 | 0.78 | F2 (0.64) | F2PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL9057442 | 0.78 | F2 (0.63) | F2PRSS1PRSS2PRSS3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1305846-C | Urea derivatives | SANTEN PHARCEUMATICAL CO LTD (JP) | 2007-03-21 | — | — | CN | claimed |
| CN-1299344-A | Novel urea derivatives | SANTEN PHARCEUMATICAL CO LTD (JP) | 2001-06-13 | — | — | CN | claimed |
| CN-1305846-C | Urea derivatives | SANTEN PHARCEUMATICAL CO LTD (JP) | 2007-03-21 | — | — | CN | disclosed |
| CN-1299344-A | Novel urea derivatives | SANTEN PHARCEUMATICAL CO LTD (JP) | 2001-06-13 | — | — | CN | disclosed |
| EP-0983232-A2 | GUANIDINYLATION REAGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052917-A2 | GUANIDINYLATION REAGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-11-26 | — | — | WO | disclosed |
| EP-0637318-B1 | PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5686564-A | Peptide derivatives corresponding to the carboxy terminal sequence of hirudin | NOVARTIS CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0693081-A1 | CYCLIC COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION | Novartis AG (CH) | 1996-01-24 | — | — | EP | disclosed |
| EP-0637318-A1 | PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN | Novartis AG (CH) | 1995-02-08 | — | — | EP | disclosed |
| WO-1994024153-A1 | CYCLIC COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION | CIBA-GEIGY AG (CH) | 1994-10-27 | — | — | WO | disclosed |
| US-5354843-A | Flanking peptides of calcitonin and processes for their manufacture | CIBA-GEIGY CORPORATION (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1993022344-A1 | PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN | CIBA-GEIGY AG (CH) | 1993-11-11 | — | — | WO | disclosed |