Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041203 | 0.98 | HSD17B10 (0.53) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL8041050 | 0.95 | HSD17B10 (0.58) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL8046336 | 0.94 | HSD17B10 (0.60) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL8040821 | 0.88 | HSD17B10 (0.49) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL9335457 | 0.87 | HSD17B10 (0.54) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL8046400 | 0.87 | ACACB (0.45) | FFAR1FFAR4LPLLIPGCA2 | |
| SCHEMBL9328232 | 0.87 | HSD17B10 (0.61) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL8433963 | 0.87 | HSD17B10 (0.61) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL9332520 | 0.86 | HSD17B10 (0.57) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL9333518 | 0.86 | HSD17B10 (0.57) | HSD17B10TSHRALDH1A1ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |