SCHEMBL8039586

SCHEMBL8039586

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nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
ALDH1A1 P00352 4/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HPGD P15428 1/20 0.38
THRB P10828 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1721382 1.00 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL13109814 0.96 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1245547 0.93 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL25170339 0.93 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL20752381 0.91 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8127216 0.90 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2335557 0.90 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30843331 0.89 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29356428 0.88 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3268370 0.88 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0753019-B1 CONCENTRATE AND LUBRICATING OIL COMPOSITION COMPRISING STAR-BRANCHED ACRYLATE AND METHACRYLATE POLYMERS ETHYL ADDITIVES CORP (US) 2000-04-12 EP claimed
EP-4747339-A1 INDUSTRIAL GEAR LUBRICANT The Lubrizol Corporation (US) 2026-05-27 EP disclosed
EP-2292668-B2 Process for preparing polymers and compositions thereof LUBRIZOL CORP (US) 2025-09-10 EP disclosed
WO-2025019655-A1 INDUSTRIAL GEAR LUBRICANT THE LUBRIZOL CORPORATION (US) 2025-01-23 WO disclosed
EP-3101096-B1 METHOD OF LUBRICATION OF TURBINES USING STAR POLYMERS LUBRIZOL CORP (US) 2023-08-16 EP disclosed
CN-110997882-B Lubricating composition containing self-assembled polymethacrylate block copolymer and ethylene-alpha-olefin copolymer 路博润公司 2023-08-08 CN disclosed
EP-3645682-B1 LUBRICATING COMPOSITION CONTAINING A SELF-ASSEMBLING POLYMETHACRYLATE BLOCK COPOLYMER AND AN ETHYLENE-ALPHA-OLEFIN COPOLYMER LUBRIZOL CORP (US) 2022-08-03 EP disclosed
US-11365367-B2 Lubricating composition for and method of lubricating an internal combustion engine THE LUBRIZOL CORPORATION (US) 2022-06-21 US disclosed
US-11359159-B2 Lubricating composition containing a self-assembling polymethacrylate block copolymer and an ethylene-α-olefin copolymer THE LUBRIZOL CORPORATION (US) 2022-06-14 US disclosed
EP-0140362-B1 ESTERS OF S-ALKYL(2-HYDROXYPHENYLTHIO)CARBOXYLIC ACIDS CIBA-GEIGY AG (CH) 1987-07-22 EP disclosed
EP-0140362-A2 Esters of S-alkyl(2-hydroxyphenylthio)carboxylic acids CIBA-GEIGY AG (CH) 1985-05-08 EP disclosed