Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4539858 | 0.94 | PPARG (0.89) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4540388 | 0.91 | PPARG (0.87) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16731516 | 0.90 | PPARG (0.86) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14977258 | 0.90 | PPARG (1.00) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16000001 | 0.90 | PPARG (0.86) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15992392 | 0.90 | PPARG (1.00) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16000000 | 0.90 | PPARG (0.86) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15992288 | 0.90 | PPARG (1.00) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8035899 | 0.90 | PPARG (1.00) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4541102 | 0.89 | PPARG (0.83) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |