Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214287 | 0.84 | CYP3A4 (0.36) | CYP3A4 | |
| SCHEMBL8040065 | 0.83 | TNKS (0.43) | TNKSTNKS2DPP4DPP8KCNH2 | |
| SCHEMBL7424938 | 0.80 | FNTA (0.47) | DPP4DPP8KCNH2CYP3A4FNTA | |
| Hydrochloric Acid SCHEMBL2328814 | 0.79 | FNTA (0.47) | DPP4DPP8KCNH2CYP3A4FNTA | |
| Hydrochloric Acid SCHEMBL2328817 | 0.79 | FNTA (0.47) | DPP4DPP8KCNH2CYP3A4FNTA | |
| SCHEMBL7482530 | 0.78 | SIRT2 (0.48) | DPP4DPP8KCNH2CYP3A4FNTA | |
| SCHEMBL7423151 | 0.78 | KDM4E (0.35) | DPP4DPP8KCNH2CYP3A4FNTA | |
| SCHEMBL7419120 | 0.78 | SIRT2 (0.48) | DPP4DPP8KCNH2CYP3A4FNTA | |
| SCHEMBL7424077 | 0.78 | KDM4E (0.35) | DPP4DPP8KCNH2CYP3A4FNTA | |
| Hydrochloric Acid SCHEMBL8040100 | 0.77 | KDM4E (0.35) | DPP4DPP8KCNH2CYP3A4FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034093-A | Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 2000-03-07 | — | — | US | disclosed |