Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040105 | 1.00 | USP2 (0.32) | USP2 | |
| SCHEMBL4397832 | 0.83 | USP2 (0.38) | USP2 | |
| SCHEMBL4397828 | 0.83 | USP2 (0.38) | USP2 | |
| SCHEMBL21838077 | 0.80 | USP2 (0.31) | USP2 | |
| SCHEMBL21837874 | 0.80 | MAPT (0.31) | USP2 | |
| SCHEMBL21838076 | 0.80 | USP2 (0.31) | USP2 | |
| SCHEMBL21837873 | 0.80 | MAPT (0.31) | USP2 | |
| SCHEMBL7628748 | 0.77 | USP2 (0.61) | USP2 | |
| SCHEMBL5711389 | 0.77 | USP2 (0.61) | USP2 | |
| SCHEMBL4397844 | 0.76 | USP2 (0.40) | USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747392-B1 | 1,2-Diazepine containing dual action inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2000-11-02 | — | — | EP | disclosed |
| US-5635504-A | Diazepine containing dual action inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 1997-06-03 | — | — | US | disclosed |
| EP-0747392-A1 | 1,2-Diazepine containing dual action inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |