Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114318 | 0.87 | KMT2A (0.61) | KDM4EALDH1A1MAPTGAAUSP2 | |
| SCHEMBL9077842 | 0.87 | KDM4E (0.58) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL18031417 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL30418756 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL18969560 | 0.83 | USP2 (0.46) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL25980683 | 0.83 | USP2 (0.50) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL18940647 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL751242 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL9333497 | 0.82 | TSHR (0.56) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL30152705 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1MAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987250-A1 | INDOLE DICARBOXYLIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |