Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | TYMP | P19971 | 5/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932396 | 0.88 | POLB (0.59) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL30536137 | 0.87 | POLB (0.53) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL17992980 | 0.87 | POLB (0.59) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL23157266 | 0.85 | POLB (0.56) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL5925303 | 0.85 | POLB (0.56) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL23056641 | 0.85 | POLB (0.56) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL5358852 | 0.85 | POLB (0.56) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14049948 | 0.84 | POLB (0.58) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL30547473 | 0.84 | POLB (0.55) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL17090840 | 0.84 | POLB (0.57) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084082-A | SOLID PHASE SYNTHESIS BY ATTACHING BETA-LACTAM HAVING NUCLEOBASE TO SOLID SUPPORT, DEPROTECTING HYDROXY GROUP, REACTING FREE HYDROXYL GROUP WITH BETA-LACTAMTIDE HAVING ACTIVATED PHOSPHITE GROUP, AND OXIDIZING | ISIS PHARMACEUTICALS, INC. (US) | 2000-07-04 | — | — | US | disclosed |
| US-5510476-A | SOLID PHASE SYNTHESIS USING AN ACIDIC SOLUTION OF THE SCAVENGER TO DEPROTECT THE 5'-HYDROXY AND NEUTRALIZE THE CARBO ANION RELEASED; HIGH YIELDS | ISIS PHARMACEUTICALS, INC. (US) | 1996-04-23 | — | — | US | disclosed |