SCHEMBL8040816

SCHEMBL8040816

C/C=C/[C@H]1CO[C@H]([C@H]2CC[C@H]([C@H]3CC[C@H](c4ccc(F)c(F)c4)CC3)CC2)OC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP5 P45974 2/20 0.32
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8971634 0.99 USP5 (0.32) USP5HDAC6
SCHEMBL9247084 0.99 USP5 (0.32) USP5HDAC6
SCHEMBL9247082 0.99 USP5 (0.32) USP5HDAC6
SCHEMBL8971628 0.99 USP5 (0.32) USP5HDAC6
SCHEMBL8971621 0.99 USP5 (0.32) USP5HDAC6
SCHEMBL8025058 0.89 CYP17A1 (0.30)
SCHEMBL9136971 0.89 CYP17A1 (0.30)
SCHEMBL9136961 0.89 CYP17A1 (0.30)
SCHEMBL8025057 0.89 CYP17A1 (0.30)
SCHEMBL8025055 0.89 CYP17A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0497176-B1 Four rings compounds and liquid crystal mixtures containing them MERCK PATENT GMBH (DE) 2000-04-05 EP disclosed
US-5478497-A For electro-optical purposes HOFFMANN-LA ROCHE INC. (US) 1995-12-26 US disclosed
EP-0497176-A2 Four rings compounds and liquid crystal mixtures containing them F. HOFFMANN-LA ROCHE AG (CH) 1992-08-05 EP disclosed