Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040821 | 0.94 | HSD17B10 (0.49) | HSD17B10TSHRFFAR1FFAR4ALDH1A1 | |
| SCHEMBL8046336 | 0.90 | HSD17B10 (0.60) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL8041050 | 0.88 | HSD17B10 (0.58) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9335411 | 0.88 | HSD17B10 (0.66) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9335275 | 0.88 | HSD17B10 (0.66) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9335482 | 0.88 | HSD17B10 (0.66) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9333038 | 0.86 | HSD17B10 (0.63) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9333071 | 0.85 | HSD17B10 (0.62) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9335925 | 0.85 | HSD17B10 (0.62) | HSD17B10TSHRFFAR1FFAR4RARB | |
| SCHEMBL9335897 | 0.85 | HSD17B10 (0.62) | HSD17B10TSHRFFAR1FFAR4RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| CN-1135515-A | Liquid crystal alkynyl tolane compound, liquid crystal composition and liquid crystal display part | CHISSO CORP (JP) | 1996-11-13 | — | — | CN | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |