Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8040985

N=C(N)c1cccc(CN2CC[C@H](NS(=O)(=O)c3cc4ncc(Cl)cc4s3)C2=O)c1.O=C(O)C(F)(F)F

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.71
PRSS1 P07477 4/20 0.71
PROC P04070 3/20 0.71
PLAT P00750 2/20 0.71
F2 P00734 6/20 0.69
PLG P00747 3/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL8040983 1.00 F10 (0.71) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7480779 0.90 F10 (0.89) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7480117 0.88 F10 (0.89) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7480111 0.88 F10 (0.89) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7476771 0.88 F10 (0.68) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7476767 0.88 F10 (0.68) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7480738 0.88 F10 (0.70) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7479748 0.88 F10 (0.70) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7562559 0.87 F10 (0.70) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7562563 0.87 F10 (0.70) F10PRSS1PROCPLATF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6034093-A Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 2000-03-07 US disclosed