SCHEMBL8040988

SCHEMBL8040988

CCC#CCc1ccc(C#Cc2cc(F)c(CCC)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 7/20 0.41
FFAR4 Q5NUL3 5/20 0.41
ACACB O00763 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046324 0.90 FFAR1 (0.40) FFAR1FFAR4ACACB
SCHEMBL8039099 0.88 FFAR1 (0.41) FFAR1FFAR4ACACB
SCHEMBL8039893 0.84 FFAR1 (0.45) FFAR1FFAR4ACACB
SCHEMBL8039120 0.83 ACACB (0.38) FFAR1FFAR4ACACB
SCHEMBL8029151 0.83 ACACB (0.35) FFAR1FFAR4ACACB
SCHEMBL8046404 0.81 ACACB (0.49) FFAR1FFAR4ACACB
SCHEMBL8042911 0.80 RARB (0.40) FFAR1FFAR4ACACB
SCHEMBL8039326 0.79 FFAR1 (0.34) FFAR1FFAR4ACACB
SCHEMBL8029353 0.78 FFAR1 (0.36) FFAR1FFAR4ACACB
SCHEMBL8029484 0.78 FFAR1 (0.42) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727473-B1 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-01-12 EP disclosed
US-5833879-A LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES CHISSO CORPORATION (JP) 1998-11-10 US disclosed
EP-0727473-A2 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-08-21 EP disclosed