Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027782 | 0.85 | PLK1 (0.93) | PLK1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30466712 | 0.85 | MEN1 (0.72) | PLK1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2025586 | 0.85 | MEN1 (0.72) | PLK1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2290164 | 0.84 | SMN1; SMN2 (0.76) | PLK1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2292518 | 0.84 | SERPINE1 (0.71) | PLK1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2273929 | 0.83 | NR1H4 (0.60) | PLK1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5936643 | 0.82 | SMN1; SMN2 (0.61) | PLK1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14075231 | 0.82 | PLK1 (0.84) | PLK1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8027764 | 0.81 | MEN1 (0.67) | PLK1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6337620 | 0.80 | PLK1 (0.60) | PLK1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |