Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137326 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AMEN1TDP1SOAT1 | |
| SCHEMBL9135172 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2AMEN1TDP1SOAT1 | |
| SCHEMBL8041519 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2KMT2AMEN1TDP1SOAT1 | |
| SCHEMBL9136269 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AMEN1TDP1SOAT1 | |
| SCHEMBL9008108 | 0.77 | KMT2A (0.58) | SMN1; SMN2KMT2AMEN1TDP1SOAT1 | |
| SCHEMBL9843936 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2KMT2AMEN1TDP1SOAT1 | |
| SCHEMBL9047310 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMEN1TDP1SOAT1 | |
| SCHEMBL9050107 | 0.76 | SOAT1 (0.54) | SMN1; SMN2SOAT1 | |
| SCHEMBL9137847 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2AMEN1TDP1SOAT1 | |
| SCHEMBL9048730 | 0.76 | SOAT1 (0.54) | SMN1; SMN2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7316129-A | — | — | None | — | — | JP | disclosed |
| EP-0874812-B1 | NOVEL 2,3,5-TRIMETHYL-4-HYDROXY ANILIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | PF MEDICAMENT (FR) | 2000-04-05 | — | — | EP | disclosed |
| JP-H07316129-A | PRODUCTION OF ALKYL THIOACETAMIDE | TAISHO PHARMACEUT CO LTD | 1995-12-05 | — | — | JP | disclosed |