Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054933 | 0.92 | MEN1 (0.38) | MEN1RAD52KMT2ACNR1CYP1A2 | |
| SCHEMBL19830975 | 0.84 | MEN1 (0.41) | MEN1RAD52KMT2ACNR1NPC1 | |
| SCHEMBL10535362 | 0.84 | CNR1 (0.37) | MEN1RAD52KMT2ACNR1CYP1A2 | |
| SCHEMBL4057097 | 0.83 | MEN1 (0.42) | MEN1RAD52KMT2ALMNA | |
| SCHEMBL4055305 | 0.76 | — | — | |
| SCHEMBL12982688 | 0.74 | CNR1 (0.42) | CNR1CYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL4062011 | 0.74 | MEN1 (0.41) | MEN1RAD52KMT2AKDM1ARCOR1 | |
| SCHEMBL5185388 | 0.73 | CYP2A6 (0.47) | MEN1RAD52KMT2AOPRM1OPRL1 | |
| SCHEMBL12981332 | 0.71 | CNR2 (0.42) | CNR1CYP2D6LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL2082072 | 0.70 | CNR1 (0.40) | CNR1CYP1A2CYP2D6CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987238-A1 | LIQUID-CRYSTALLINE COMPOUNDS HAVING BICYCLO 1.1.1]PENTANE STRUCTURE, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2000-03-22 | — | — | EP | disclosed |