SCHEMBL8041945

SCHEMBL8041945

CSc1cc(S(F)(F)(F)(F)F)ccc1-c1oncc1C(=O)C1CC1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8043245 0.82 JAK2 (0.30)
SCHEMBL8045015 0.78 HCRTR1 (0.33)
SCHEMBL9119031 0.76
SCHEMBL8041950 0.73 DHODH (0.36)
SCHEMBL8725745 0.73 HCRTR1 (0.34)
SCHEMBL8101250 0.72 MELK (0.36)
SCHEMBL8726295 0.72 MELK (0.36)
SCHEMBL9116747 0.72 MEN1 (0.42)
SCHEMBL8891259 0.71 MAP2K1 (0.34)
SCHEMBL8893509 0.71 KMT2A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5849928-A Herbicidal isoxazole and 2-cyano-1,3-dione compounds RHONE-POULENC AGRICULTURE LIMITED (GB) 1998-12-15 US claimed
JP-10036206-A None JP disclosed
US-6140528-A ALKYL PENTAFLUOROSULFANYL-SUBSTITUTED-BENZOATES RHONE-POULENC AGRICULTURE LTD (GB) 2000-10-31 US disclosed
US-6013805-A USED AS HERBICIDES RHONE-POULENC AGRICULTURE LTD (GB) 2000-01-11 US disclosed
US-5849928-A Herbicidal isoxazole and 2-cyano-1,3-dione compounds RHONE-POULENC AGRICULTURE LIMITED (GB) 1998-12-15 US disclosed
JP-H1036206-A NEW HERBICIDE RHONE POULENC AGRICULTURE LTD 1998-02-10 JP disclosed