⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043724 | 0.81 | — | — | |
| SCHEMBL12053909 | 0.79 | — | — | |
| SCHEMBL5439184 | 0.78 | — | — | |
| SCHEMBL6547798 | 0.72 | — | — | |
| SCHEMBL662994 | 0.72 | — | — | |
| SCHEMBL3562167 | 0.69 | — | — | |
| SCHEMBL8423128 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL517125 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL11786194 | 0.67 | — | — | |
| SCHEMBL11427573 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103435525-A | Preparation method of ezetimibe | ASYMCHEM LAB TIANJIN CO LTD | 2013-12-11 | — | — | CN | claimed |
| CN-103435525-A | Preparation method of ezetimibe | ASYMCHEM LAB TIANJIN CO LTD | 2013-12-11 | — | — | CN | disclosed |
| US-6027849-A | SUBSTRATE COATED WITH PHOTOSENSITIVE LAYER COMPRISING A RADIATION ABSORBING MATERIAL AND POLYGLYCIDYL AZIDE CAPABLE SOLVENT-FREE RELIEF IMAGE DEVELOPMENT; PRINTING PLATES | IMATION CORP. (US) | 2000-02-22 | — | — | US | disclosed |
| EP-0562952-B1 | Ablative imageable element | MINNESOTA MINING & MFG (US) | 1996-12-27 | — | — | EP | disclosed |
| EP-0562952-A1 | Ablative imageable element | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |