Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 5/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.30 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419737 | 0.81 | TYMP (0.42) | NT5ETYMPDUTP2RY14CYP3A4 | |
| SCHEMBL5978909 | 0.81 | TYMP (0.42) | NT5ETYMPDUTP2RY14CYP3A4 | |
| SCHEMBL4081760 | 0.79 | NT5E (0.39) | NT5ETYMPDUTP2RY14CYP3A4 | |
| SCHEMBL2472505 | 0.77 | NT5E (0.41) | NT5ETYMPDUTP2RY14P2RY2 | |
| SCHEMBL13837115 | 0.74 | TYMP (0.45) | NT5ETYMPDUTP2RY14CYP3A4 | |
| SCHEMBL6362952 | 0.74 | NT5E (0.39) | NT5ETYMPDUTP2RY14P2RY2 | |
| SCHEMBL8058513 | 0.73 | NT5E (0.39) | NT5ETYMPDUTP2RY14CYP3A4 | |
| SCHEMBL5977396 | 0.73 | TYMP (0.47) | TYMPP2RY14P2RY2P2RY4 | |
| SCHEMBL13575501 | 0.73 | P2RY2 (0.54) | NT5ETYMPDUTP2RY14CYP3A4 | |
| SCHEMBL5977841 | 0.72 | TYMP (0.47) | TYMPP2RY14P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497875-B1 | 2' MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2000-03-22 | — | — | EP | claimed |