Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066639 | 1.00 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL28225058 | 0.84 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL28224391 | 0.84 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL1870654 | 0.84 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL11027935 | 0.82 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL10791168 | 0.81 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL13672306 | 0.80 | TSHR (0.44) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL2640220 | 0.80 | TSHR (0.44) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL10245222 | 0.78 | TSHR (0.43) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL7850044 | 0.78 | TSHR (0.43) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325378-A | Cannabinoid receptor 1 antagonists/inverse agonists and uses thereof | 柯巴斯医药有限公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-111410663-B | Preparation of double-target point synergistic compound and application of compound in field of diseases related to multiple myeloma | 北京桦冠医药科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-111410663-A | Preparation of double-target point synergistic compound and application of compound in field of diseases related to multiple myeloma | 北京桦冠医药科技有限公司 | 2020-07-14 | — | — | CN | disclosed |
| EP-1000041-A1 | 1,3-DIAZA- HETEROCYCLES AND THEIR USE AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005131-A1 | 1,3-DIAZA- HETEROCYCLES AND THEIR USE AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1999-02-04 | — | — | WO | disclosed |