Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343615 | 0.83 | CYP17A1 (0.56) | CYP17A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL16104509 | 0.80 | CYP17A1 (0.53) | CYP17A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL4612023 | 0.80 | CYP17A1 (0.53) | CYP17A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL27989815 | 0.78 | CYP2A6 (0.74) | CYP17A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL28244556 | 0.77 | RARB (0.50) | CYP17A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL5877900 | 0.77 | CYP17A1 (0.50) | CYP17A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL282801 | 0.76 | — | — | |
| SCHEMBL8309627 | 0.75 | CYP17A1 (0.56) | CYP17A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL112385 | 0.75 | HRH3 (0.61) | CYP17A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL5828167 | 0.75 | CYP17A1 (0.56) | CYP17A1CYP11B1CYP11B2CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976744-A1 | Amide, carbamate, and urea derivatives having glutamate receptor function potentiating activity | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |