Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924110 | 0.86 | GRM2 (0.70) | GRM2 | |
| SCHEMBL921945 | 0.86 | GRM2 (0.75) | GRM2 | |
| SCHEMBL8053278 | 0.82 | GRM2 (0.74) | GRM2 | |
| SCHEMBL924146 | 0.81 | GRM2 (0.71) | GRM2 | |
| SCHEMBL8045719 | 0.80 | GRM2 (0.57) | GRM2 | |
| SCHEMBL921967 | 0.80 | GRM2 (1.00) | GRM2 | |
| SCHEMBL3652536 | 0.79 | GRM2 (0.68) | GRM2 | |
| SCHEMBL922899 | 0.74 | GRM2 (1.00) | GRM2 | |
| SCHEMBL12907972 | 0.72 | GRM2 (0.58) | GRM2 | |
| SCHEMBL748766 | 0.72 | GRM2 (0.81) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009062676-A2 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |