SCHEMBL8043709

SCHEMBL8043709

CC(C)CCCC1CCC(c2ccc(-c3cc(F)c(C(F)(F)F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.34
FASN P49327 1/20 0.34
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
GRM2 Q14416 1/20 0.32
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8034581 0.89 ESR2 (0.34) APPCYP3A4CYP2C9GRM2
SCHEMBL13002533 0.87 FASN (0.37) APPFASNCYP3A4CYP2C9PDK2
SCHEMBL8043715 0.87 KDM1A (0.36) APPCYP3A4CYP2C9
SCHEMBL8044836 0.87 AKR1C3 (0.42) APPFASNCYP3A4CYP2C9
SCHEMBL8044832 0.86 APP (0.33) APPCYP3A4CYP2C9GRM2
SCHEMBL8042991 0.86 PDE2A (0.32)
SCHEMBL8052370 0.86 FASN (0.35) APPFASNCYP3A4CYP2C9GRM2
SCHEMBL8034226 0.85 PDE2A (0.32)
SCHEMBL13002531 0.85 CYP2C9 (0.41) APPFASNCYP3A4CYP2C9GRM2
SCHEMBL13002323 0.84 FASN (0.35) APPFASNCYP3A4CYP2C9PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733692-B1 Liquid crystalline compound, liquid crystal composition containing the same, and display device CHISSO CORP (JP) 2000-06-14 EP disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed