Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042785 | 0.96 | PRSS1 (0.41) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL8033906 | 0.92 | APP (0.42) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2110631 | 0.87 | PRSS1 (0.51) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2110635 | 0.87 | PRSS1 (0.51) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109988 | 0.84 | PRSS1 (0.49) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109993 | 0.84 | PRSS1 (0.49) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109694 | 0.79 | PRSS1 (0.47) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109697 | 0.79 | PRSS1 (0.47) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL8046395 | 0.79 | PRSS1 (0.46) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2109791 | 0.79 | PRSS1 (0.54) | PRSS1PRSS2PRSS3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067202-A1 | SPIROPIPERIDINES FOR USE AS TRYPTASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-28 | — | — | WO | disclosed |