Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.35 |
| ▸ | MICA | Q29983 | 1/20 | 0.35 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046206 | 0.87 | CYP11B1 (0.38) | AKR1C3AKR1C2APPFASN | |
| SCHEMBL8052370 | 0.87 | FASN (0.35) | AKR1C3AKR1C2CYP3A4CYP2C9APP | |
| SCHEMBL8052400 | 0.87 | HTR2C (0.35) | AKR1C3AKR1C2HTR2CCETP | |
| SCHEMBL8034044 | 0.86 | GRM2 (0.41) | CYP3A4CYP2C9APPFASN | |
| SCHEMBL8997321 | 0.86 | CYP2C9 (0.45) | AKR1C3AKR1C2CYP3A4CYP2C9APP | |
| SCHEMBL8997327 | 0.86 | CYP2C9 (0.45) | AKR1C3AKR1C2CYP3A4CYP2C9APP | |
| SCHEMBL8562849 | 0.86 | HTR2C (0.43) | CYP2C9P2RY14HTR2CADRB3ADRA2B | |
| SCHEMBL8044836 | 0.86 | AKR1C3 (0.42) | AKR1C3AKR1C2CYP3A4CYP2C9APP | |
| SCHEMBL9809581 | 0.85 | CYP3A4 (0.46) | AKR1C3AKR1C2CYP3A4CYP2C9APP | |
| SCHEMBL9319293 | 0.85 | CYP3A4 (0.46) | AKR1C3AKR1C2CYP3A4CYP2C9APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733692-B1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | CHISSO CORP (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0733692-A1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |