Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.62 |
| ▸ | S1PR5 | Q9H228 | 14/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 11/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269683 | 0.88 | S1PR1 (0.50) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL772529 | 0.77 | S1PR1 (1.00) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL772248 | 0.76 | S1PR1 (1.00) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL803889 | 0.75 | PLAT (0.45) | S1PR1S1PR5 | |
| SCHEMBL1334375 | 0.73 | S1PR1 (0.75) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL10269631 | 0.73 | S1PR1 (0.64) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL15384213 | 0.72 | S1PR1 (0.81) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1336650 | 0.72 | S1PR1 (0.67) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL3749519 | 0.72 | S1PR1 (0.98) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL13415797 | 0.71 | S1PR1 (1.00) | S1PR1S1PR5S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071460-A1 | PYRAZOLE OXADIAZOLE DERIVATIVES AS S1P1 AGONISTS | MERCK SERONO SA (CH) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071460-A1 | PYRAZOLE OXADIAZOLE DERIVATIVES AS S1P1 AGONISTS | S1PR1, S1PR3, S1PR2 | S1PR1 1/4885S1PR5 4/4885S1PR4 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.