Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045473 | 1.00 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP17A1HSD17B14ESR1 | |
| SCHEMBL8047023 | 0.96 | CYP11B1 (0.36) | CYP11B1CYP11B2CYP17A1HSD17B14ESR1 | |
| SCHEMBL8047028 | 0.96 | CYP11B1 (0.36) | CYP11B1CYP11B2CYP17A1HSD17B14ESR1 | |
| SCHEMBL8046104 | 0.95 | CYP11B1 (0.40) | CYP11B1CYP11B2CYP17A1ESR1ESR2 | |
| SCHEMBL8046110 | 0.95 | CYP11B1 (0.40) | CYP11B1CYP11B2CYP17A1ESR1ESR2 | |
| SCHEMBL8047054 | 0.93 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP17A1HSD17B14ESR1 | |
| SCHEMBL8047050 | 0.93 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP17A1HSD17B14ESR1 | |
| SCHEMBL8045841 | 0.88 | CYP17A1 (0.34) | CYP11B1CYP11B2CYP17A1HSD17B14CYP3A4 | |
| SCHEMBL8045847 | 0.88 | CYP17A1 (0.34) | CYP11B1CYP11B2CYP17A1HSD17B14CYP3A4 | |
| SCHEMBL8044198 | 0.88 | CYP17A1 (0.40) | CYP11B1CYP11B2CYP17A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643119-B1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-6030546-A | FERROELECTRIC PHASE; LOW VISCOSITY;, THERMOSENSITIVITY OVER A BROAD AND EXHIBITS A LARGE TILT ANGLE AND A HIGH-SPEED RESPONSE PROPERTY;CHEMICAL INTERMEDIATES FOR PESTICIDES, DRUGS AND LIQUID CRYSTALS; BORIDING AND HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5707547-A | CONTAINING FLUORINATED BENZENE OR NAPHTHALENE RINGS AND/OR NITROGEN CONTAINING HETEROCYCLES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0643119-A1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |