Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 3/20 | 0.40 |
| ▸ | PTGFR | P43088 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049606 | 1.00 | NPSR1 (0.55) | NPSR1POLBHTTL3MBTL1MAPT | |
| SCHEMBL8045579 | 1.00 | NPSR1 (0.55) | NPSR1POLBHTTL3MBTL1MAPT | |
| SCHEMBL27165029 | 0.90 | NPSR1 (0.52) | NPSR1POLBHTTL3MBTL1MAPT | |
| SCHEMBL27165133 | 0.90 | NPSR1 (0.52) | NPSR1POLBHTTL3MBTL1MAPT | |
| SCHEMBL6562859 | 0.88 | NPSR1 (0.74) | NPSR1POLBHTTL3MBTL1MAPT | |
| SCHEMBL22831474 | 0.88 | NPSR1 (0.74) | NPSR1POLBHTTL3MBTL1MAPT | |
| SCHEMBL18150761 | 0.85 | POLB (0.73) | NPSR1POLBHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL30781902 | 0.85 | POLB (0.73) | NPSR1POLBHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL16971277 | 0.83 | MAPT (0.48) | POLBHTTL3MBTL1MAPTCYP1A2 | |
| SCHEMBL16971278 | 0.83 | MAPT (0.48) | POLBHTTL3MBTL1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133275-A | ALPHA 1 ADRENORECEPTOR ANTAGONISTS; TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER UROLOGICAL DISEASES E.G., BLADDER OUTLET OBSTRUCTION), NEUROGENIC BLADDER AND GYNECOLOGICAL SYNDROMES, E.G., DYSMENORRHEA; UTERINE MUSCLE RELAXANTS | ABBOTT LABORATORIES (US) | 2000-10-17 | — | — | US | disclosed |