Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815895 | 0.90 | PPARG (0.81) | PPARGPPARA | |
| SCHEMBL8056831 | 0.90 | PPARG (0.81) | PPARGPPARA | |
| SCHEMBL7815200 | 0.90 | PPARG (0.85) | PPARGPPARA | |
| SCHEMBL7815897 | 0.89 | PPARG (0.83) | PPARGPPARA | |
| SCHEMBL8057867 | 0.88 | PPARG (0.76) | PPARGPPARA | |
| SCHEMBL13649244 | 0.88 | PPARG (0.78) | PPARGPPARA | |
| SCHEMBL9393956 | 0.87 | PPARG (0.74) | PPARGPPARA | |
| SCHEMBL8061183 | 0.87 | PPARG (0.75) | PPARGPPARA | |
| SCHEMBL8045890 | 0.86 | PPARG (0.70) | PPARGPPARA | |
| SCHEMBL9086955 | 0.86 | PPARG (0.71) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000938-A1 | Heterocyclic compounds as pharmaceuticals | SMITHKLINE BEECHAM PLC (GB) | 2000-05-17 | — | — | EP | disclosed |
| US-6048883-A | HYPOGLYCEMIC AGENT | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0648212-A1 | HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001420-A1 | HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 1994-01-20 | — | — | WO | disclosed |