Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28876712 | 0.86 | IDO1 (0.44) | MAPTALDH1A1CYP1A2CYP2D6KDM4E | |
| SCHEMBL29922600 | 0.84 | IDO1 (0.49) | MAPTHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL3650531 | 0.84 | IDO1 (0.49) | MAPTHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL21799867 | 0.81 | MAPT (0.39) | MAPTHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL29922400 | 0.81 | MAPT (0.39) | MAPTHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL21799823 | 0.79 | MAPT (0.38) | MAPTHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL17006480 | 0.78 | HTT (0.57) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL21799996 | 0.77 | MAPT (0.39) | MAPTHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL29922652 | 0.77 | MAPT (0.39) | MAPTHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL21800072 | 0.77 | HDAC3 (0.39) | MAPTHDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663446-B1 | Electrochemical assay method and novel p-phenylenediamine compound | MOCHIDA PHARM CO LTD (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5609749-A | FUNCTIONS AS ELECTRON MEDIATOR, MODULATION OF OXIDATION-REDUCTION ENZYME ACTIVITY IS MEASURED, IMMUNOASSAY | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0195363-B1 | HAIR-DYEING COMPOSITION | Henkel Kommanditgesellschaft auf Aktien (DE) | 1990-10-31 | — | — | EP | disclosed |