Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046202 | 0.89 | CYP2C9 (0.32) | CYP2C9CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL8034752 | 0.88 | EPHX2 (0.36) | APPGRM2FASNCYP3A4CYP2C9 | |
| SCHEMBL8034044 | 0.88 | GRM2 (0.41) | APPGRM2FASNCYP3A4CYP2C9 | |
| SCHEMBL8043174 | 0.87 | EPHX2 (0.32) | CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL8044832 | 0.87 | APP (0.33) | APPGRM2CYP3A4CYP2C9CHRM2 | |
| SCHEMBL8046242 | 0.86 | — | — | |
| SCHEMBL8052370 | 0.86 | FASN (0.35) | APPGRM2FASNCYP3A4CYP2C9 | |
| SCHEMBL8045502 | 0.85 | EPHX2 (0.31) | CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL17175207 | 0.84 | CYP2C9 (0.37) | GRM2FASNCYP3A4CYP2C9 | |
| SCHEMBL8049212 | 0.83 | CHRM2 (0.31) | CHRM2CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733692-B1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | CHISSO CORP (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0733692-A1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |