Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039093 | 0.95 | KCNH2 (0.49) | KCNH2FFAR1FFAR4TSHRHSD17B10 | |
| SCHEMBL8046363 | 0.95 | KCNH2 (0.53) | KCNH2FFAR1FFAR4TNK2ACACB | |
| SCHEMBL8046345 | 0.90 | KCNH2 (0.52) | KCNH2FFAR1FFAR4HSD17B10TNK2 | |
| SCHEMBL8041073 | 0.90 | KCNH2 (0.44) | KCNH2FFAR1TSHRHSD17B10ACACB | |
| SCHEMBL8040007 | 0.89 | TSHR (0.41) | KCNH2FFAR1FFAR4TSHRHSD17B10 | |
| SCHEMBL8042875 | 0.86 | KCNH2 (0.40) | KCNH2FFAR1FFAR4TSHRHSD17B10 | |
| SCHEMBL8042902 | 0.85 | KCNH2 (0.47) | KCNH2FFAR1ACACBGRM5MEN1 | |
| SCHEMBL8046422 | 0.85 | KCNH2 (0.40) | KCNH2FFAR1FFAR4TNK2GRM5 | |
| SCHEMBL8042893 | 0.84 | FFAR1 (0.46) | KCNH2FFAR1FFAR4TSHRHSD17B10 | |
| SCHEMBL8040194 | 0.84 | MCHR1 (0.48) | KCNH2FFAR1FFAR4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |