Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496900 | 0.99 | EDNRA (0.64) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7496869 | 0.97 | EDNRA (0.66) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8043446 | 0.95 | EDNRA (0.59) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7494119 | 0.93 | EDNRA (0.60) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8590715 | 0.91 | EDNRA (0.58) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3838490 | 0.90 | EDNRA (0.58) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8434697 | 0.88 | EDNRA (0.58) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7506376 | 0.86 | EDNRA (0.51) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3835089 | 0.86 | EDNRA (0.53) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3837125 | 0.85 | EDNRA (0.70) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143774-A | DRUGS AS HYPOTENSIVE AGENTS | HOECHST MARION ROUSSEL (FR) | 2000-11-07 | — | — | US | disclosed |