Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | MGAM | O43451 | 3/20 | 0.34 |
| ▸ | SI | P14410 | 3/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046851 | 1.00 | CYP2D6 (0.40) | CYP2D6GAAMGAMSIMGAM2 | |
| SCHEMBL8045846 | 0.99 | CYP2D6 (0.39) | CYP2D6GAAMGAMSIMGAM2 | |
| SCHEMBL8045850 | 0.99 | CYP2D6 (0.39) | CYP2D6GAAMGAMSIMGAM2 | |
| SCHEMBL8046643 | 0.92 | SRC (0.36) | CYP2D6GAAMEN1KMT2AMAPT | |
| SCHEMBL8046647 | 0.92 | SRC (0.36) | CYP2D6GAAMEN1KMT2AMAPT | |
| SCHEMBL8051235 | 0.92 | NPC1 (0.40) | CYP2D6GAAMGAMSIMGAM2 | |
| SCHEMBL8051233 | 0.92 | NPC1 (0.40) | CYP2D6GAAMGAMSIMGAM2 | |
| SCHEMBL8046296 | 0.91 | CYP2D6 (0.35) | CYP2D6PDE3BPDE3AP2RY12MAOB | |
| SCHEMBL8046289 | 0.91 | CYP2D6 (0.35) | CYP2D6PDE3BPDE3AP2RY12MAOB | |
| SCHEMBL8047655 | 0.91 | CYP2D6 (0.35) | CYP2D6MAPTPDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643119-B1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5707547-A | CONTAINING FLUORINATED BENZENE OR NAPHTHALENE RINGS AND/OR NITROGEN CONTAINING HETEROCYCLES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0643119-A1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |