SCHEMBL8047033

SCHEMBL8047033

[CH2]CCCOC1CCC(OCCCCCCCCCC)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 3/20 0.42
EPHX2 P34913 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
RECQL P46063 2/20 0.38
GLA P06280 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
BLM P54132 1/20 0.38
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.36
CA1 P00915 8/20 0.35
CA2 P00918 8/20 0.35
CA9 Q16790 7/20 0.35
CA12 O43570 3/20 0.35
CA7 P43166 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11451186 0.89 GBA1 (0.50) GBA1EPHX2ALDH1A1TDP1RECQL
Ammonia Solution, Strong SCHEMBL14359739 0.87 GBA1 (0.48) GBA1EPHX2ALDH1A1TDP1RECQL
SCHEMBL5987408 0.87
Ammonia Solution, Strong SCHEMBL4076473 0.85 EPHX2 (0.45) GBA1EPHX2ALDH1A1TDP1RECQL
SCHEMBL130850 0.85 SPHK1 (0.32)
SCHEMBL126309 0.85
SCHEMBL128965 0.83
SCHEMBL27639590 0.82 GBA1 (0.38) GBA1EPHX2ALDH1A1TDP1RECQL
SCHEMBL17058984 0.82 GBA1 (0.44) GBA1EPHX2ALDH1A1TDP1RECQL
SCHEMBL14318707 0.82 GBA1 (0.44) GBA1EPHX2ALDH1A1TDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6106999-A SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS MITSUI CHEMICALS (JP) 2000-08-22 US disclosed