SCHEMBL8047260

SCHEMBL8047260

N#Cc1cccc(O)c1C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 17/20 0.50
PGR P06401 3/20 0.45
PDK2 Q15119 1/20 0.39
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25983090 0.85 AR (0.46) ARPGRPDK2
SCHEMBL5512574 0.82 TDP1 (0.45) ARPDK2
SCHEMBL27871845 0.80 AR (0.36) ARPGR
SCHEMBL16951107 0.80 AR (0.36) ARPGR
SCHEMBL17030752 0.80 AR (0.39) ARPGRPDK2ESR2
SCHEMBL3911267 0.78 AR (0.46) ARPGR
SCHEMBL1994873 0.78 AR (0.41) ARPGRPDK2
SCHEMBL29378798 0.78 AR (0.41) ARPGRPDK2
SCHEMBL5228912 0.76 TSHR (0.54) ARPGR
SCHEMBL16954302 0.76 AR (0.40) ARPGRPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0606858-B1 Liquid crystal compositions and liquid crystal display devices CHISSO CORP (JP) 2000-04-26 EP claimed
US-5985170-A OF SUPERTWISTED NEMATIC (STN) MODE, CYANOPHENOL, (TRIFLUOROMETHYL)CYANOPHENOL, AND CYANODIFLUOROPHENOL, CONTROLLING A VOLTAGE HOLDING RATIO CHISSO CORPORATION (JP) 1999-11-16 US claimed
EP-0606858-A1 Liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 1994-07-20 EP claimed
EP-0606858-B1 Liquid crystal compositions and liquid crystal display devices CHISSO CORP (JP) 2000-04-26 EP disclosed
US-5985170-A OF SUPERTWISTED NEMATIC (STN) MODE, CYANOPHENOL, (TRIFLUOROMETHYL)CYANOPHENOL, AND CYANODIFLUOROPHENOL, CONTROLLING A VOLTAGE HOLDING RATIO CHISSO CORPORATION (JP) 1999-11-16 US disclosed
US-5723065-A CONDENSED HETEROCYCLE AND AROMATIC AMINE, ALIPHATIC AMINE AND FLUOROCYANOPHENOL CHISSO CORPORATION (JP) 1998-03-03 US disclosed
EP-0606858-A1 Liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 1994-07-20 EP disclosed