SCHEMBL8047520

SCHEMBL8047520

CCC1CCC(c2ccc(C(=O)Oc3ccc(F)c(F)c3)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.42
MAPT P10636 3/20 0.41
ALDH1A1 P00352 3/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
IDO1 P14902 1/20 0.38
MCHR1 Q99705 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
CCR1 P32246 1/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
DGAT1 O75907 1/20 0.35
SOAT1 P35610 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA1A P35348 1/20 0.35
USP5 P45974 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8052087 0.91 CYP2C9 (0.55) CYP2C9MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL11131803 0.91 IDO1 (0.41) CYP2C9MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL11131804 0.91 IDO1 (0.41) CYP2C9MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL8027355 0.89 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL12566105 0.89 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL8052270 0.89 CYP2C9 (0.47) CYP2C9MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL8037722 0.88 CYP2C9 (0.46) CYP2C9MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL13325815 0.88 CYP2C9 (0.46) CYP2C9MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL7516179 0.87 CYP2C9 (0.38) CYP2C9MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL20152468 0.87 CYP2C9 (0.38) CYP2C9MAPTALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728829-B1 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-05-03 EP disclosed
US-5698136-A LOW TEMPERATURE COMPATIBILITY, CHEMICAL STABILITY CHISSO CORPORATION (JP) 1997-12-16 US disclosed
EP-0728829-A2 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1996-08-28 EP disclosed