SCHEMBL8047593

SCHEMBL8047593

CC(=O)CC(=O)C(C)C.CCCCC(=O)CC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
KDM6B O15054 1/20 0.42
KDM5C P41229 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
PHF8 Q9UPP1 1/20 0.42
KDM2A Q9Y2K7 1/20 0.42
HAO1 Q9UJM8 1/20 0.40
CES1 P23141 2/20 0.39
CES2 O00748 2/20 0.38
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
FAAH O00519 1/20 0.36
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11685972 0.88 HAO1 (0.45) HAO1CES1CES2KMT2AMEN1
SCHEMBL27634581 0.86 HAO1 (0.44) HAO1CES1CES2KMT2AMEN1
SCHEMBL93265 0.85 KDM4E (0.54) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL29046835 0.83 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL4262073 0.83 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL30534804 0.83 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL29035555 0.83 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28661429 0.83 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL29586686 0.83 HAO1 (0.54) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL9342282 0.83 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077455-B1 NON AQUEOUS CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS BV (NL) 2024-06-12 EP disclosed
EP-4359482-A1 NON AQUEOUS CROSSLINKABLE COMPOSITION Allnex Netherlands B.V. (NL) 2024-05-01 EP disclosed
CN-113544181-B Non-aqueous crosslinkable compositions 湛新荷兰有限公司 2023-08-08 CN disclosed
US-20230183521-A1 NON-AQUEOUS CROSS-LINKABLE COMPOSITION ALLNEX RESINS (CHINA) CO., LTD. (CN) 2023-06-15 US disclosed
US-20230026705-A1 NON AQUEOUS CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS B.V. (NL) 2023-01-26 US disclosed
WO-2022268669-A1 NON AQUEOUS CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS B.V. (NL) 2022-12-29 WO disclosed
EP-3941957-A1 NON-AQUEOUS CROSSLINKABLE COMPOSITION Allnex Netherlands B.V. (NL) 2022-01-26 EP disclosed
WO-2021122978-A1 NON AQUEOUS CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS B.V. (NL) 2021-06-24 WO disclosed
WO-2020187928-A1 NON-AQUEOUS CROSSLINKABLE COMPOSITION ALLNEX NETHERLANDS BV (NL) 2020-09-24 WO disclosed
US-6084026-A MIXTURES OF HYDROXYL-CONTAINING POLYOLS, ISOCYANATE CROSSLINKERS, CATALYSTS, CARBOXYLIC OR SULFONIC ACIDS AND EXTENDERS(BETA-DICARBONYL COMPOUNDS, ALPHA-HYDROXY OR FUSED AROMATIC OR NITROGEN HETEROCYCLIC BETA-HYDROXY COMPOUNDS) ROHM AND HAAS COMPANY (US) 2000-07-04 US disclosed
EP-0882748-A2 Coating compositions having extented pot life and short cure time ROHM AND HAAS COMPANY (US) 1998-12-09 EP disclosed