Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672390 | 0.68 | PRSS1 (0.47) | NPY5RPRSS1PRSS2PRSS3 | |
| SCHEMBL6544408 | 0.67 | NOTUM (0.41) | NPY5R | |
| SCHEMBL736523 | 0.67 | AKT1 (0.44) | NPY5R | |
| SCHEMBL6543311 | 0.66 | AKT1 (0.46) | NPY5R | |
| SCHEMBL6544534 | 0.66 | NOTUM (0.48) | NPY5R | |
| SCHEMBL29661970 | 0.66 | AKT1 (0.46) | NPY5R | |
| Hydrochloric Acid SCHEMBL6215953 | 0.66 | AKT1 (0.43) | NPY5R | |
| Hydrochloric Acid SCHEMBL6218341 | 0.65 | AKT1 (0.45) | NPY5R | |
| Hydrochloric Acid SCHEMBL1760929 | 0.65 | NOTUM (0.47) | NPY5R | |
| SCHEMBL29662021 | 0.64 | AKT1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067202-A1 | SPIROPIPERIDINES FOR USE AS TRYPTASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-28 | — | — | WO | disclosed |