Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052173 | 0.96 | SPHK1 (0.47) | SPHK1SPHK2 | |
| SCHEMBL8037908 | 0.95 | SPHK1 (0.46) | SPHK1SPHK2 | |
| SCHEMBL8055238 | 0.92 | SPHK1 (0.33) | SPHK1SPHK2 | |
| SCHEMBL8047566 | 0.88 | SPHK1 (0.46) | SPHK1SPHK2HRH3RARBTSHR | |
| SCHEMBL8054980 | 0.88 | — | — | |
| SCHEMBL8050104 | 0.88 | SPHK1 (0.35) | SPHK1SPHK2 | |
| SCHEMBL8052450 | 0.88 | SPHK1 (0.43) | SPHK1SPHK2HRH3RARBTSHR | |
| SCHEMBL8052446 | 0.88 | SPHK1 (0.43) | SPHK1SPHK2HRH3RARBTSHR | |
| SCHEMBL8047557 | 0.87 | SPHK1 (0.35) | SPHK1SPHK2 | |
| SCHEMBL8049793 | 0.86 | CYP2C9 (0.36) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728829-B1 | Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5698136-A | LOW TEMPERATURE COMPATIBILITY, CHEMICAL STABILITY | CHISSO CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0728829-A2 | Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1996-08-28 | — | — | EP | disclosed |