Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.35 |
| ▸ | ESR1 | P03372 | 13/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049430 | 1.00 | PDE3B (0.35) | PDE3BPDE3AP2RY12ESR2ESR1 | |
| SCHEMBL8049882 | 0.87 | PDE3B (0.38) | PDE3BPDE3AP2RY12ESR2ESR1 | |
| SCHEMBL8049887 | 0.87 | PDE3B (0.38) | PDE3BPDE3AP2RY12ESR2ESR1 | |
| SCHEMBL8049562 | 0.87 | PDE3B (0.34) | PDE3BPDE3AP2RY12ESR2ESR1 | |
| SCHEMBL8049556 | 0.87 | PDE3B (0.34) | PDE3BPDE3AP2RY12ESR2ESR1 | |
| SCHEMBL8036027 | 0.87 | CYP17A1 (0.37) | ESR2ESR1FGFR1FGFR2CYP17A1 | |
| SCHEMBL8036030 | 0.87 | CYP17A1 (0.37) | ESR2ESR1FGFR1FGFR2CYP17A1 | |
| SCHEMBL8047797 | 0.86 | CYP17A1 (0.39) | ESR2ESR1FGFR1FGFR2CYP17A1 | |
| SCHEMBL8047794 | 0.86 | CYP17A1 (0.39) | ESR2ESR1FGFR1FGFR2CYP17A1 | |
| SCHEMBL8036314 | 0.85 | PDE3B (0.33) | PDE3BPDE3AP2RY12ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643119-B1 | Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-6030546-A | FERROELECTRIC PHASE; LOW VISCOSITY;, THERMOSENSITIVITY OVER A BROAD AND EXHIBITS A LARGE TILT ANGLE AND A HIGH-SPEED RESPONSE PROPERTY;CHEMICAL INTERMEDIATES FOR PESTICIDES, DRUGS AND LIQUID CRYSTALS; BORIDING AND HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5707547-A | CONTAINING FLUORINATED BENZENE OR NAPHTHALENE RINGS AND/OR NITROGEN CONTAINING HETEROCYCLES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |