Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | TACR2 | P21452 | 2/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | SHBG | P04278 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | TST | Q16762 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175632 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL396014 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10762522 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL395650 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL168031 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL9678943 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Octane SCHEMBL9724037 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL167114 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL21963890 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL7649256 | 1.00 | ESR1 (0.65) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4211 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113931003-A | Thermal sublimation transfer printing coating with uniform temperature rise and functional micromolecule preparation process thereof | 绍兴高塔新材料科技有限公司 | 2022-01-14 | — | — | CN | claimed |
| CN-111704577-A | Preparation method of cinacalcet hydrochloride | 华北水利水电大学 | 2020-09-25 | — | — | CN | claimed |
| CN-107915656-A | The preparation method of methanesulfonic acid safinamide | 孙婷婷 | 2018-04-17 | — | — | CN | claimed |
| US-9120715-B2 | Alkylation of aromatic substrates | TOTAL PETROCHEMICALS FRANCE (FR) | 2015-09-01 | — | — | US | claimed |
| US-8940467-B2 | Toner | CANON KABUSHIKI KAISHA (JP) | 2015-01-27 | — | — | US | claimed |
| US-20140206917-A1 | Alkylation of Aromatic Substrates | TOTAL PETROCHEMICALS FRANCE (FR) | 2014-07-24 | — | — | US | claimed |
| US-20130244165-A1 | TONER | CANON KABUSHIKI KAISHA (JP) | 2013-09-19 | — | — | US | claimed |
| US-8536395-B2 | Catalyst with an ion-modified binder | FINA TECHNOLOGY, INC. (US) | 2013-09-17 | — | — | US | claimed |
| US-20120095250-A1 | CATALYST WITH AN ION-MODIFIED BINDER | FINA TECHNOLOGY, INC. (US) | 2012-04-19 | — | — | US | claimed |
| WO-2009046370-A2 | BIOFUEL PRODUCTION | BIO ARCHITECTURE LAB, INC. (US) | 2009-04-09 | — | — | WO | claimed |
| US-6552209-B1 | Such as reacting tantalum pentachloride with tertbutylamine and pyridine; stripping solvent and extracting into tetra-hydrofuran; adding extract to fresh in situ prepared lithium diethylamine solution; high yield and purity | AIR PRODUCTS AND CHEMICALS, INC. | 2003-04-22 | — | — | US | claimed |
| US-6384246-B1 | ALCOHOL SOLVENT EXTRACTION, ADSORPTION, FURTHER EXTRACTION WITH ALIPHATIC HYDROCARBON AND CHLORINATED HYDROCARBON SOLVENT | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2002-05-07 | — | — | US | claimed |
| US-5354860-A | Process for making pure S-timolol hemihydrate | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-10-11 | — | — | US | claimed |
| EP-0440684-B1 | NOVEL S-TIMOLOL DERIVATIVE AND PROCESS FOR ITS PREPARATION | LEIRAS OY (FI) | 1994-09-28 | — | — | EP | claimed |
| EP-0440684-A1 | NOVEL S-TIMOLOL DERIVATIVE AND PROCESS FOR ITS PREPARATION. | HUHTAMAEKI YHTHYMAE OY (FI) | 1991-08-14 | — | — | EP | claimed |
| WO-1990004592-A1 | NOVEL S-TIMOLOL DERIVATIVE AND PROCESS FOR ITS PREPARATION | Huhtamäki Oy (FI) | 1990-05-03 | — | — | WO | claimed |
| US-4752651-A | FROM AN ALIPHATIC HETERO COMPOUND USING AN AROMATIC DILUENT AND A NONZEOLITIC MOLECUAR SIEVE CATALYST | UNION CARBIDE CORPORATION (US) | 1988-06-21 | — | — | US | claimed |
| JP-11116580-A | — | — | None | — | — | JP | disclosed |
| US-3932479-A | BRONCHODILATOR, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
| US-3931256-A | Chemical process for production of bile acids | INTELLECTUAL PROPERTY DEVELOPMENT CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |