Oxirane

Oxirane

SCHEMBL8050218

C1CO1.CCCCCCCC/C=C\CCCCCCCCOP(=O)(O)O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 13/20 0.79
LPAR2 Q9HBW0 11/20 0.79
LPAR1 Q92633 11/20 0.79
ENPP2 Q13822 3/20 0.57
LPAR4 Q99677 2/20 0.51
LPAR5 Q9H1C0 2/20 0.51
CES2 O00748 1/20 0.51
LPAR6 P43657 1/20 0.51
TRPV1 Q8NER1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxirane SCHEMBL8053351 0.98 LPAR3 (0.77) LPAR3LPAR2LPAR1ENPP2LPAR4
SCHEMBL193119 0.92 LPAR3 (0.93) LPAR3LPAR2LPAR1ENPP2
SCHEMBL304775 0.92 LPAR3 (0.93) LPAR3LPAR2LPAR1ENPP2
SCHEMBL193118 0.92 LPAR3 (0.93) LPAR3LPAR2LPAR1ENPP2
SCHEMBL19821294 0.92 LPAR3 (0.93) LPAR3LPAR2LPAR1ENPP2
SCHEMBL23016698 0.92 LPAR3 (0.93) LPAR3LPAR2LPAR1ENPP2
SCHEMBL7781151 0.92 LPAR3 (0.93) LPAR3LPAR2LPAR1ENPP2
SCHEMBL4981351 0.92 LPAR3 (0.93) LPAR3LPAR2LPAR1ENPP2
SCHEMBL38660089 0.92 LPAR3 (0.93) LPAR3LPAR2LPAR1ENPP2
SCHEMBL4981337 0.92 LPAR3 (0.93) LPAR3LPAR2LPAR1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0557024-B1 Polyolefin fiber HERCULES INC (US) 2000-05-03 EP claimed
US-5545481-A FIBER WITH ANTISTATIC FINISH OF ORGANIC METAL PHOSPHATE AND SOLUBILIZER HERCULES INCORPORATED (US) 1996-08-13 US claimed
US-5540953-A POLYOLEFIN STAPLE FABRIC WITH AN ANTISTATIC FINISH HERCULES INCORPORATED (US) 1996-07-30 US claimed
EP-0557024-B1 Polyolefin fiber HERCULES INC (US) 2000-05-03 EP disclosed
US-5545481-A FIBER WITH ANTISTATIC FINISH OF ORGANIC METAL PHOSPHATE AND SOLUBILIZER HERCULES INCORPORATED (US) 1996-08-13 US disclosed
US-5540953-A POLYOLEFIN STAPLE FABRIC WITH AN ANTISTATIC FINISH HERCULES INCORPORATED (US) 1996-07-30 US disclosed
EP-0557024-A1 Polyolefin fiber HERCULES INCORPORATED (US) 1993-08-25 EP disclosed