Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.65 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097170 | 0.87 | PPARA (0.81) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL10687273 | 0.87 | PPARA (0.63) | PPARAPPARGS1PR4S1PR1S1PR3 | |
| SCHEMBL8057272 | 0.87 | PPARA (0.63) | PPARAPPARGS1PR4S1PR1S1PR3 | |
| SCHEMBL10688594 | 0.85 | PPARA (0.60) | PPARAS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL10686096 | 0.85 | PPARA (0.60) | PPARAS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL8617055 | 0.83 | CYP4F2 (0.52) | PPARAS1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9453304 | 0.83 | PPARA (0.66) | PPARAPPARGS1PR1S1PR3S1PR5 | |
| SCHEMBL11094600 | 0.83 | PPARA (0.74) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL11093079 | 0.82 | PPARA (0.73) | PPARAPPARGTTRCYP1A2CYP2C8 | |
| SCHEMBL10685541 | 0.81 | PPARA (0.83) | PPARAPPARGTTRCYP1A2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763527-B1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-04-26 | — | — | EP | disclosed |
| EP-0763527-A1 | Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-03-19 | — | — | EP | disclosed |