Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 4/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785073 | 1.00 | CYP2C19 (0.44) | CYP2C19SCN4ADPP4F2HRH1 | |
| SCHEMBL8067055 | 1.00 | CYP2C19 (0.44) | CYP2C19SCN4ADPP4F2HRH1 | |
| Hydrochloric Acid SCHEMBL11222348 | 0.98 | CYP2C19 (0.43) | CYP2C19SCN4ADPP4F2HRH1 | |
| Hydrochloric Acid SCHEMBL462457 | 0.98 | CYP2C19 (0.43) | CYP2C19SCN4ADPP4F2HRH1 | |
| SCHEMBL12789451 | 0.88 | CYP2C19 (0.42) | CYP2C19SCN4ADPP4F2HRH1 | |
| SCHEMBL13250518 | 0.86 | CYP2C19 (0.41) | CYP2C19SCN4ADPP4F2HRH1 | |
| SCHEMBL21096603 | 0.84 | SCN4A (0.42) | SCN4A | |
| SCHEMBL28547360 | 0.84 | SCN4A (0.42) | SCN4A | |
| SCHEMBL18482959 | 0.81 | SCN4A (0.38) | CYP2C19SCN4ADPP4F2HRH1 | |
| SCHEMBL21096430 | 0.81 | PTGS1 (0.43) | CYP2C19SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060617-A | REACTING AN ALKALI METAL HYDRIDE AND ALKALI METAL AMIDES WITH A SUBSTITUTED AMINE IN AN ETHER SOLVENT IN ABSENCE OF AN ELECTRON CARRIER TO PRODUCE AN ALKALI METAL AMIDE FREE OF ORGANIC CONTAMINANTS | FMC CORPORATION (US) | 2000-05-09 | — | — | US | claimed |
| US-5726308-A | High purity formulations of highly substituted lithium amide bases | FMC CORPORATION (US) | 1998-03-10 | — | — | US | claimed |
| US-6060617-A | REACTING AN ALKALI METAL HYDRIDE AND ALKALI METAL AMIDES WITH A SUBSTITUTED AMINE IN AN ETHER SOLVENT IN ABSENCE OF AN ELECTRON CARRIER TO PRODUCE AN ALKALI METAL AMIDE FREE OF ORGANIC CONTAMINANTS | FMC CORPORATION (US) | 2000-05-09 | — | — | US | disclosed |
| US-5726308-A | High purity formulations of highly substituted lithium amide bases | FMC CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1997002210-A2 | CONTAMINANT FREE ORGANOMETALLIC AMIDE COMPOSITIONS AND PROCESSES FOR MAKING SAME | FMC CORPORATION (US) | 1997-01-23 | — | — | WO | disclosed |