Sugi Predict

Sugi Predict / Compounds / SCHEMBL8050672

SCHEMBL8050672

SCHEMBL8050672

CCCCCC[Si](Cl)(Cl)CCCCl

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.57
▸ ALDH1A1 P00352 2/20 0.57
▸ TDP1 Q9NUW8 1/20 0.48
▸ THRB P10828 1/20 0.40
▸ FAAH O00519 2/20 0.39
▸ PLA2G1B P04054 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33
▸ RAD52 P43351 1/20 0.33
▸ ATG4B Q9Y4P1 1/20 0.33
▸ DNM1 Q05193 5/20 0.32
▸ LMNA P02545 2/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ SLC22A1 O15245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11307324 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL131055 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL2763894 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL132353 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL21817819 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL134147 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL14645782 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL11313336 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL135669 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL11315982 0.89 TSHR (0.50) TSHRALDH1A1THRBDNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 — — US claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 — — EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 — — US claimed
EP-1006136-A1 Solid-liquid phase interfacial polymerisation DOW CORNING CORPORATION (US) 2000-06-07 — — EP disclosed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 — — US disclosed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 — — EP disclosed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 — — US disclosed